Research

Looking out for the next big breakthrough in the field of medicine

Thyroid Disorders and Diabetes Mellitus

Dr. Sayantan Ray (MD) – Post Doctoral Fellow
Dr. Sujoy Ghosh (DM, FRCP, FACE, FICP) – Associate Professor: Dept. of Endocrinology, IGME&R, Kolkata

About: Thyroid diseases and diabetes mellitus are the two most common endocrine disorders encountered in clinical practice. They mutually influence each other and associations between both conditions have long been reported. There is a deep underlying relation between diabetes mellitus and thyroid dysfunction. A plethora of studies have evidenced an array of complex intertwining biochemical, genetic, and hormonal malfunctions mirroring this pathophysiological association. read more

Onco–Nephrology – The New Kid on the Block

Dr. Arghya Majumdar (MD, DNB, MRCP, Higher Sp. Training in Nephro (UK) – Director & Head, Dept. of Nephrology, AMRI Hospitals, Kolkata.

About: In Oncology, new diagnostic techniques and therapies have emerged, which has improved the outcomes for many types of cancer. It is not surprising that the life expectancy in the population with cancer is increasing. Cancers may have varied manifestations, electrolyte disorders, like hypercalcaemia and syndrome of inappropriate ADH secretion (SIADH) or paraneoplastic glomerulopathies, which are not related directly to cancer infiltration. read more

Neuroprotection in PICU

Dr. Prabhas Prasun Giri MD (Paed), MRCPch (UK) – Junior Consultant, Paediatric Intensive Care Unit, AMRI Mukundapur

About: Paediatric Intensive Care is one of the fastest growing sub specialities in the world. The ultimate aim of a PICU is to give the sick babies a neurologically intact future. Neurological cases cater form a bulk of PICU patients. Therefore, a good neuroprotective strategy should be offered to all of the PICU patients with a special emphasis on the neurologically damaged child. read more

PET CT in PUO

Dr. Deepanjan Mitra, DNB (Nuclear Medicine) MNAMS, FASNC–Head, AMRI Institute of Nuclear Medicine & PET CT, AMRI Hospitals Dhakuria, Kolkata

About: Pyrexia of unknown origin is quite frustrating both for patients and the treating physicians for delay in diagnosis and initiation of appropriate treatment hereby escalating the treatment cost and prolonging hospital stays. There is a battery of investigations in the work up of PUO however many are often non-contributory. Despite several investigations, almost 30 – 50 % of PUOs remain undiagnosed and pose a challenge. read more

A study of Frozen Shoulder in patients with and without Diabetes Mellitus Type 2

Dr. Ritwika Mallik, MBBS, DNB – DNB Post Graduate Trainee
Dr. Sujoy Ghosh, DM, FRCP, FACE, FICP – Consultant Endocrinologist
Dr. Kamal Sinha, MD – Consultant Physiatrist
Dr. R.K Dutta Roy, MD – Senior Consultant, Department of Medicine, AMRI Hospitals, Dhakuria

About: The prevalence of Frozen shoulder is 2 to 5 % but an increased prevalence has been reported in patients with Diabetes Mellitus. Our aim was to find the prevalence of frozen shoulder in patients with Diabetes Mellitus, to compare the severity of frozen shoulder in patients with Diabetes Mellitus type 2 (DM) and without Diabetes Mellitus (NDM). We also meant to look for an association between glycaemic control and microvascular complications among diabetic patients with and without frozen shoulder. read more

Increased Urine Albumin: Creatinine Ratio on admission is an early biomarker of acute kidney injury more so in the critically ill patients with sepsis

Dr. Surupa Basu – Department of Biochemistry, Institute of Child Health, Kolkata

Dr. Arghya Majumdar – Department of Nephrology, AMRI Hospitals, Kolkata

About: In critically ill patients, early diagnosis of septic acute kidney injury can help clinicians instil specific therapeutic measures that may increase the chances of survival. This study investigated the potential of urine albumin to delineate septic acute kidney injury on admission to intensive care unit (ICU). This study was carried out in a 43 bed ICU of a tertiary care hospital. Albumin Creatinine ratio was measured within 6 hours of admission on random urine samples. read more

Occurrence and risk factors of peripheral artery disease in Type-2 Diabetes: An Eastern India perspective

Dr. Anirban Majumdar – Department of Medicine, KPC Medical College, Kolkata

Dr. Deep Dutta & Dr. Sujoy Ghosh – Department of Endocrinology & Metabolism, Institute of Post Graduate Medical Examination & Research (IPGMER) and Seth Sukhlal Karnani Memorial (SSKM) Hospital, Kolkata

Dr. Sagarika Mukherjee – Department of Endocrinology, Institute of Diabetes and Hormonal Disorders, AMRI Hospitals, Kolkata

About: Studies have suggested lower prevalence of peripheral artery disease (PAD) among Indians compared to the west. Data on Indian (PAD) is available from Southern and Western India. No data is available on PAD among type-2 diabetes (T2DM) patients from Eastern India. India is an ethnically diverse country, and data from one part may not be representative for the rest. Hence this study aimed to find the prevalence and risk factors associated with PAD among T2DM patients in Calcutta. read more

Free Iron Status and Insulin Resistance in Type 2 Diabetes: Analyzing the probable role of a Peanut Protein

Dr. Souvik Sen – Department of Medicine, Mugneeram Ramkowar Bangur Hospital, Desapran Sasmal Road, Kolkata
Dr. Sumanta Kumar Ghatak & Dr. Kamalika Sen – Department of Chemistry, University of Calcutta, APC Road, Kolkata
Dr. Dipanjali Majumdar – National Environmental Engineering Research Institute, Kolkata Zonal Laboratory, E.M Bypass, Kolkata
Dr. Basudev Bhattacharya – Department of Biochemistry, Institute of Post Graduate Medical Education and Research, Kolkata

About: South Asian population is known to have an increased predisposition to type 2 diabetes mellitus (T2DM), which turns out to be an important health concern in this region. 11.7% of people in Kolkata suffer from Type 2 diabetes mellitus and the prevalence is on a rise. Anemia is also present in the region as a significant public health problem, having a prevalence of greater than 40% in South Asia. read more

VKA vs NOAC – Role in Atrial Fibrillation

Dr. Tapas Banerjee, MD – Consultant Cardiologist, AMRI Hospitals, Mukundapur, Kolkata

About: A 76-year-old, obese, type 2 diabetic, hypertensive and hypothyroid male patient had sustained anterior wall Myocardial Infarction 5 years back for which PTCA was done. Presently he had LVEF of 40%. His creatinine was 1.5. One year back he developed syncope. Holter monitoring at that time revealed intermittent atrial fibrillation with slow ventricular rate and Mobitz type 2 A-V block. PPI was done. At that time MRI brain showed multiple lacunar infarcts as well as gliosis. read more

Year in Review 2015 from New England Journal of Medicine

Dr. Subhash Kr. Todi, MD, MRCP (UK) – Director & Head, Department of Critical Care, AMRI Hospitals, Kolkata

About:
  1. A randomized trial of Intra-arterial Treatment for acute Ischemic Stroke (MR CLEAN) – Jan 1. NEJM
  2. Stent-Retriever Thrombectomy after intravenous t-PA vs t-PA Alone in Stroke – June 11. NEJM
  3. Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging selection – March 12 NEJM

read more

An Unusual Cause of Haematemesis in an Infant

Dr. Bhaswati C Acharyya, DCH, MD, DNB (Paed & Gastro), MRCPCH (UK), MRCP (Edin) – Consultant and Lead; Dept. of Paediatric Gastroenterology, AMRI Mukundapur

About: Haematemesis in infancy is an uncommon entity. It is often self-limiting. However, it may cause considerable alarm to the parents as well as the clinician. Septicaemia, coagulopathy, necrotising enterocolitis, Mallory Weiss tear are few causes which predominate. Haematemesis due to gastroduodenal polyp is a very rare aetiology to find in infants. Among the polyps, hamartomatous polyp and hyperplastic polyp might be encountered in infancy1. read more

Pulmonary Rheumatoid nodules associated with Leflunomide therapy

Dr. Sujoy Ghosh, DM, FRCP, FACE, FICP – Associate Professor: Dept. of Endocrinology, IGME&R, Kolkata and Consultant Endocrinologist, AMRI Hospital, Dhakuria, Kolkata

About: Rheumatoid nodules are the commonest extra-articular manifestation of rheumatoid arthritis. Accelerated nodulosis in rheumatoid arthritis (RA) during therapy has been reported with methotrexate, etanercept, infliximab and rarely Leflunomide. We report pulmonary rheumatoid nodulosis in a 77-year-old lady with rheumatoid arthritis who was treated with Leflunomide. read more

A follow-up case of post-thymectomy Myasthenic Crisis improved by serial Therapeutic Plasma Exchange – a case report

Dr. Chikam Maity & Dr. Rathin Biswas – Department of Immuno-Haematology and Blood Transfusion Medicine, Medical College Hospital

Dr. Prasun Bhattacharya – Head, Department of Blood Transfusion Medicine, AMRI Hospitals, Kolkata

About: Myasthenia gravis is an autoimmune disorder of neuromuscular transmission associated with quantitative and qualitative deficiency of acetylcholine receptors (AChR). Myasthenia Gravis (MG) cases with worsening features and respiratory insufficiency, have set IV IG a frequently advised treatment option for its wider and easy availability, even sometimes, without excluding the possibility of IgA deficiency. read more

Find and Book Appointments with Doctors